Job Description

E11 Bio is on a mission to reach a whole-brain human connectome. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit focused research organization organized under the Convergent Research umbrella and located in Alameda, California. We are pursuing blue-sky neuroscience research yet operate like a nimble, tight-knit start-up. Read our technology roadmap for more. E11 is seeking an enthusiastic Research Associate to support the team in reliably and reproducibly generating and processing biological samples for our moonshot mission. Responsibilities Processing of brain tissue and hydrogel samples (including sample sectioning and trimming) Optimization and development of sample processing technologies Evaluation and quality control of brain samples by fluorescence microscopy Coordination and documentation of sample processing pipeline, including sample hand-off Experimental validation of new, cutting edge staining reagents in tissue and hydrogel preparations Thorough and professional digital documentation of biological sample and reagent preparation Close collaboration with an interdisciplinary team to facilitate experiments based on your work Development and testing of lab automation systems Misc. laboratory duties when needed, including but not necessarily limited to: preparing pre-weighted stocks and liquid buffers for expansion microscopy experiments, tracking and maintaining experimental reagents, assisting with expansion microscopy sample preparation, etc. Required Qualifications Bachelor degree or equivalent focusing on biological and/or medical sciences (molecular biology, biotechnology, bioengineering, etc.) Experience with molecular biology and microscopy laboratory techniques (e.g. biological sample preparation, immunofluorescence, expansion microscopy, etc.) Strong organizational and communication skills and a predisposition to maintain accurate records. A willingness and proven history of quickly picking up new processes and adapting to changing needs. Preferred Qualifications ~ Experience with fluorescence microscopy ~ Experience with tissue sectioning ~2 years laboratory experience as a research associate or equivalent. ~ A track record of independently executing well-defined lines of experimental research You will love this job if.... You are excited about consistently and reliably preparing the biological samples that are the foundation of our scientific process, including tissue sectioning, clearing and staining, and performing fluorescence microscopy on world-class, cutting-edge instruments. You are excited by working within a tight-knit team, facilitating the work of your colleagues and accelerating science through high-impact experiments. You are eager to learn. We offer An opportunity to help change the world and work with some of the most talented and collaborative experts across scientific fields. An opportunity to gain experience with field-leading light microscopy techniques. Excellent medical, dental, and vision insurance through a PPO plan; parental leave. Generous time off + paid holidays. Ample healthy and energizing food including free lunches. Wellness allowance for fitness and wellness activities. $68,000 - $76,000 a year E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.

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